Rémi Goupil

Dr Rémi Goupil est un néphrologue et clinicien-chercheur de l'hôpital du Sacré-Coeur de Montréal. Il a complété ses études médicales à l'université de Montréal et une formation complémentaire de recherche clinique sur l'hypertension résistante et endocrinienne à l'université du Queensland (Brisbane, Australie) en 2015. Il a également complété une maitrise en sciences biomédicales à l'université de Montréal en 2016. Durant sa formation, il a reçu de nombreuses bourses et prix, notamment des Fonds de recherche du Québec - Santé (FRQ-S) et de la Société québécoise d'hypertension artérielle(SQHA). En 2018, il est devenu clinicien-chercheur du FRQS et a reçu la bourse Jacques-de-Champlain de la SQHA. Son programme de recherche s'intéresse à la prédiction et aux complications de l'hypertension artérielle et des maladies rénales, en particulier sur la pression artérielle centrale et la rigidité artérielle. Ses travaux récents ont été publiés dans des revues à haut impact telles que JAMA Network Open, Hypertension, Journal of Hypertension, CMAJ, Canadian Journal of Cardiology et Nephrology Dialysis Transplantation. Au cours des dernières années, il obtenu à titre d'investigateur principal plusieurs subventions majeures de la part des Instituts de recheche en santé du Canada, de la Fondation Coeur+ AVC, de la Fondation du rein du Canada, de la Société québécoise d'hypertension artérielle et du Fonds de recherche en santé - Québec. De plus, Dr Goupil a reçu le New Investigator Lectureship Award de la Société canadienne de néphrologie en 2020, le prix du Nouveau Chercheur de la Société québécoise d'hypertension artérielle en 2022 et le prix du Jeune Néphrologue de l'année de la Société québécoise de néphrologie en 2022.

• Maîtrise en sciences biomédicales, Université de Montréal (2014-2016)
• Formation complémentaire, Université du Queensland, Brisbane, Australie (2014-2015)
• DES en néphrologie, Université de Montréal (2008-2013)
• Doctorat enmédecine, Université de Montréal (2004-2008)
• Baccalauréat en sciences biomédicales, Université de Montréal (2000-2003)

Hundemer GL, Agharazii M, Madore F, Vaidya A, Leung AA, Kline GA, Crean AM, Shaw JL, Ramsay T, Hametner B, Wassertheurer S, Sood MM, Hiremath S, Rizicka M, Goupil R. Subclinical Primary Aldosteronism and Cardiovascular Health: A Population-Based Cohort Study. Circulation. 2023 Nov 30. doi: 10.1161/CIRCULATIONAHA.123.066389. 

Desbiens LC, Tennankore KK, Goupil R, Perl J, Trinh E, Chan CT, Nadeau-Fredette AC. Outcomes of Integrated Home Dialysis Care: Results From the Canadian Organ Replacement Register. Am J Kidney Dis. 2023 Aug 30:S0272-6386(23)00779-5.

Desbiens LC, Nadeau-Fredette AC, Madore F, Agharazii M, Goupil R. The Impact of Repeated Automated Office Blood Pressure Measurements on Cardiovascular Risk Prediction. Hypertension. 2023 Oct;80(10):2209-2217. doi: 10.1161/HYPERTENSIONAHA.123.21510. Epub 2023 Aug 24.

Bui TV, Picone DS, Schultz MG, Peng X, Black JA, Dwyer N, Roberts-Thomson P, Adams H, Chen CH, Cheng HM, Pucci G, Wang J, Goupil R, Sharman JE. Accuracy of cuff blood pressure and systolic blood pressure amplification. Hypertens Res. 2023 Aug;46(8):1961-1969.

Goupil R, Nadeau-Fredette AC, Prasad B, Hundemer GL, Suri R, Beaubien-Souligny W, Agharazii M. CENtral blood pressure Targeting: A pragmatic RAndomized triaL in advanced Chronic Kidney Disease (CENTRAL-CKD): a clinical research protocol. Can J Kidney Health Dis. 2023 May 6;10:20543581231172407.

Hundemer G, Imsirovic H, Kendzerska T, Vaidya A, Leung A, Kline G, Goupil R, Madore F, Agharazii M, Knoll G, Sood M. (2023) Screening Rates for Primary Aldosteronism among Hypertensive Adults with Obstructive Sleep Apnea: A Retrospective Population-Based Study. Am J Hypertens. 2023 Feb 24:hpad022. 

Sannier G, Nicolas A, Dubé M, Marchitto L, Nayrac M, Tastet O, Tauzin A, Lima-Barbosa R, Laporte M, Cloutier R, Flores AS, Boutin M, Gong SY, Benlarbi M, Ding S, Bourassa C, Gendron-Lepage G, Medjahed H, Goyette G, Brassard N, Ortega-Delgado GG, Niessl J, Gokool L, Morrisseau C, Arlotto P, Rios N, Tremblay C, Martel-Laferrière V, Prat A, Bélair J, Beaubien-Souligny W, Goupil R, Nadeau-Fredette AC, Lamarche C, Finzi A, Suri RS, Kaufmann DE (2023). A third SARS-CoV-2 mRNA vaccine dose in people receiving hemodialysis overcomes B cell defects but elicits a skewed CD4+ T cell profile. Cell Rep Med. 2023 Mar 21;4(3):100955.

Desbiens LC, Goulamhoussen N, Fortier C, Bernier-Jean A, Agharazii M, Goupil R (2022). Enhancing central blood pressure accuracy through statistical modelling: A proof-of-concept study. Front Cardiovasc Med. 2022 Nov 23;9:1048507.

Desbiens LC, Fortier C, Nadeau-Fredette AC, Madore F, Hametnet B, Wassertheurer S, Agharazii M, Goupil R (2022). Prediction of Cardiovascular Events by Pulse Waveform Parameters: Analysis of CARTaGENE. J Am Heart Assoc. 2022 Sep 6;11(17):e026603.

Collister D*, Herrington G, Delgado L, Whitlock R, Tennankore K, Tangri N, Goupil R, Nadeau-Fredette AC, Davison SN, Wald R, Walsh M. (2022) Patient views regarding cannabis use in chronic kidney disease and kidney failure: a survey study. Nephrol Dial Transplant. 2022 Jul 26:gfac226. 

Abbaoui Y, Fortier C, Desbiens LC, Lamarche F, Nadeau-Fredette AC, Madore F, Agharazii M, Goupil R (2022). Accuracy Difference of Noninvasive Blood Pressure Measurements by Sex and Height. JAMA Netw Open. 2022 Jun 1;5(6):e2215513. 

Goupil R, Agharazii M (2022). Reply to: Inaccuracy of blood pressure measurement: the mysterious role of arterial stiffness. J Hypertens. 2022 Jan 1;40(1):194-195.

Hundemer G, Imsirovic H, Vaidya A, Yozamp N, Goupil R, Madore F, Agharazii M, Knoll G, Sood M. (2022) Screening Rates for Primary Aldosteronism among Individuals with Hypertension plus Hypokalemia: A Population-Based Retrospective Cohort Study. Hypertension. 2022 Jan;79(1):178-186. 

Paré M, Goupil R, Fortier C, Mac-Way F, Madore F, Hametner B, Wassertheurer S, Schultz M, Sharman J, Agharazii M (2022). Increased excess pressure after creation of an arteriovenous fistula in end stage renal disease. Am J Hypertens. 2022 Feb 1;35(2):149-155. 

Fortier C, Garneau CA, Paré M, Obeid H, Duval K, Goupil R, Agharazii M (2021). Modulation of arterial stiffness gradient by acute administration of nitroglycerin. Front Physiol. 2021 Dec 15;12:774056. 

Michaud A, Vadeboncoeur A, Cloutier L, Goupil R (2021). The feasibility of home self-assessment of vital signs and symptoms: a new key to telehealth for individuals? Int J Med Inform. 2021 Nov;155:104602. doi: 10.1016/j.ijmedinf.2021.104602. Epub 2021 Sep 28.

Kowalski C, Yang K, Charron T, Doucet M, Hatem R, Kouz R, Palisaitis D, Schampaert E, Terriault P, Tessier P, Goupil R. Inaccuracy of brachial blood pressure and its potential impact on treatment and aortic blood pressure estimation. J Hypertens. 2021 Dec 1;39(12):2370-2378. 

Morin C, Gionest I, Laurin LP, Goupil R, Nadeau-Fredette AC. Risk of Hospitalization, Technique Failure, and death with increased training duration in Three- days a week Home Hemodialysis Training. Hemodial Int. 2021 Oct;25(4):457-464.

Goupil R, Benlarbi M, Beaubien-Souligny W, Nadeau-Fredette AC, Chatterjee D, Goyette G, Gunaratnam L, Lamarche C, Tom A, Finzi A, Suri RS. Short-term antibody response afer 1 dose of BNT162b2 vaccine in patients receiving hemodialysis. CMAJ. 2021 May 12:cmaj.210673. doi: 10.1503/cmaj.210673. Online ahead of print.

Obeid H, Fortier C, Garneau CA, Paré M, Boutouyrie, Bruno RM, Khettab H, Goupil R, Agharazii M (2020). Radial-Digital pulse wave velocity: a non-invasive method for assessing stiffness of peripheral small arteries. Am J Physiol Heart Circ Physiol. 2021 Jan 22.

Lamarche F, Agharazii M, Madore F, Goupil R (2021). Prediction of Cardiovascular Events by Type I Central Systolic Blood Pressure: A Prospective Study. Hypertension. 2021 Feb;77(2):319-327.

Dupuis ME, Laurin LP, Goupil R, Bénard V, Pichette M, Lafrance JP, Elftouh N, Pichette V, Nadeau-Fredette AC (2020). Arteriovenous Fistula Creation and Glomerular Filtration Rate in Advanced Kidney Disease: a Matched Cohort Study. Kidney360 November 2020, 10.34067/KID.0005072020

Collister D, Pohl K, Herrington G, Lee SF, Rabbat C, Tennankore K, Zimmermann D, Tangri N, Wald R, Manns B, Suri RS, Nadeau Fredette AC, Goupil R, Silver SA, Walsh M For the DISCO-RLS Investigators (2020). The DIalysis Symptom COntrol-RestlessLegs Syndrome (DISCO-RLS) trial: A protocol for a randomized crossover placebocontrolled blinded trial. Can J Kidney Health Dis. 2020 Nov 26;7:2054358120968959.

Dupuis ME, Nadeau-Fredette AC, Madore F, Agharazii M, Goupil R (2020). Glomerular hyperfiltration improves cardiovascular risk prediction in healthy individuals. JAMA Netw Open. 2020 Apr 1;3(4):e202377.

Khalili M, Lepeytre F, Guertin JR, Goupil R, Troyanov S, Bouchard J, Madore F (2019). Impact of Updated Recommendation on Aspirin Use for Primary Prevention of Cardiovascular Disease: a Population-Based Survey. CMAJ Open 2020 Jan 28;8(1):E41-E47.

Desbiens LC, Goupil R, Mac-Way F (2019). Predictive value of quantitative ultrasound parameters for fractures in individuals with and without early chronic kidney disease: A population-based analysis of CARTaGENE. Bone 2020 Jan;130:115120.

Desbiens LC, Goupil R, Madore F, Mac-Way F (2019). Incidence of fractures in middle-aged individuals with early CKD: A population-based analysis of CARTaGENE. Nephrol Dial Transplant. 2020 Jan 17.

Paré M, Goupil R, Fortier C, Mac-Way F, Madore F, Marquis K, Hametner B, Wassertheurer S, Schultz MG, Sharman JE, Agharazii M (2019). Determinants of increased central excess pressure in dialysis: role of dialysis modality and arteriovenous fistula. Am J Hypertens. 2019 Aug 17. pii: hpz136. doi: 10.1093/ajh/hpz136. [Epub ahead of print]

Fortier C, Côté G, Mac-Way F, Goupil R, Desbiens LC, Desjardins MP, Marquis K, Hametner B, Wassertheurer S, Schultz MG, Sharman JE, Agharazii M (2019). Prognostic Value of Carotid and Radial Artery Reservoir-Wave Parameters in End-Stage Renal Disease. J Am Heart Assoc. 2019 Jul 2;8(13):e012314

Desjardins MP, Sidibé A, Fortier C, Mac-Way F, De Serres S, Larivière R, Spronck B, Goupil R, Agharazii M (2019). Impact of kidney transplantation on aortic stiffness and aortic stiffness index β0. J Hypertens. 2019 Jul;37(7):1521-1528.

Desbiens LC, Goupil R, Sibidé A, Madore F, Mac-Way F* (2019). Fracture status in middle-aged individuals with early CKD: Cross-sectional analysis of the CARTaGENE survey. Osteoporos Int 2019 (Epub Feb 22nd 2019)

R. Goupil*, M. Lamarre-Cliche, M. Vallée (2018). The 2017 ACC/AHA versus Hypertension Canada High Blood Pressure Guidelines and Potential Implications. Canadian Journal of Cardiology. 2018 May;34(5):665-669.

F. Lamarche, M. Agharazii, AC. Nadeau-Fredette, F. Madore, R. Goupil* (2018). Central Blood Pressure, Statins and LDL-cholesterol: A Mediation Analysis. Hypertension. 2018 Mar;71(3):415-421.

F. Lepeytre, PL. Lavoie, S. Troyanov, F. Madore, R. Goupil* (2018). Uric acid association with pulsatile and steady components of central and peripheral blood pressures. J Hypertens. 2018 Mar;36(3):495-501.

R. Goupil, D. Dupuis, M. Agharazii, P. Hamet, S. Troyanov, F. Madore* (2017). Central blood pressures in early chronic kidney disease: an analysis of CARTaGENE. Nephrol Dial Transplant. 2017 Jun 1;32(6):976-983.

F. Lepeytre, M. Ghannoum, H. Amman, D. Gauvreau, F. Madore, S. Troyanov, R. Goupil, J. Bouchard* (2017). Formulas for calculating osmolarity and osmolal gap: a study of diagnostic study.  Am J Kidney Dis. 2017 May 31. pii: S0272-6386(17)30670-4.

A. Bernier-Jean, W. Beaubien-Souligny, R. Goupil, F. Madore, S. Troyanov, J. Bouchard* (2017). Diagnosis and outcomes of acute kidney injury using surrogate and multiple imputation methods for missing preadmission creatinine values. BMC Nephrol. 2017 Apr 28;18(1):141.

R. Goupil*, D. Dupuis, S. Troyanov, F. Madore, M. Agharazii (2016). Heart rate dependent and independent effects of beta-blockers on central hemodynamic parameters: a propensity score analysis. Journal of Hypertension. 2016 Aug;34(8):1535-43.

S. Monticone, F. Satoh, AS. Dietz, R. Goupil, K. Lang, F. Pizzolo, RD. Gordon, M. Reincke, M. Stowasser, P. Mulatero* (2016). Clinical management and outcomes of adrenal haemorrhage following adrenal vein sampling in primary aldosteronism. Hypertension. 2016 Jan;67(1):146-52.

R. Goupil, M. Wolley, J. Ungerer, B. McWhinney, K. Mukai, M. Naruse RD. Gordon, M. Stowasser* (2015). Plasma metanephrine aids adrenal venous sampling in combined aldosterone and cortisol over-secretion: a case report. Endocrinol Diabetes Metab Case Rep. 2015;2015:150075

R. Goupil, S. Fountoulakis, RD. Gordon, M. Stowasser* (2015).  Urinary clonidine suppression testing for the diagnosis of pheochromocytoma.  Journal of Hypertension. 2015 Nov;33(11):2286-93.

R. Goupil, D. Cowley, M. Wolley, AH. Ahmed, RD. Gordon, S. M. Stowasser* (2015).  The utility of renal venous renin studies in selection of patients with renal artery stenosis for angioplasty: A retrospective study.  Journal of Hypertension 2015 2015 Sep;33(9):1931-8.

R. Goupil, M. Wolley, AH. Ahmed, RD. Gordon, M. Stowasser* (2015).  Does concomitant autonomous adrenal cortisol overproduction have the potential to confound the interpretation of adrenal venous sampling in primary aldosteronism?  Clin Endocrinol (Oxf). 2015 Oct;83(4):456-61.

R. Goupil, AC. Nadeau-Fredette, V. Royal, A. Dugas, JP. Lafrance* (2015).  An unusual initial presentation of lupus nephritis as a renal mass.  Case reports in Nephrology  2015;2015:231974. Epub 2015 Jan 8.

R. Goupil, A. Bonnardeaux, A. Boucher, S. Collette, D. Ouimet, L. Sénécal, D. Tran, M. Vallée* (2014).  Difficulty of Patient Selection in a Combined Heart-Kidney Transplant: A Case Report. Experimental and Clinical Transplantation.  2014 Jun;12(3):273-6. Epub 2014 Feb 25.

R. Goupil, AC. Nadeau-Fredette, KK Tennankore, JM. Bargman* (2014).  Peritonitis caused by veillonella species and Eggerthella lenta in peritoneal dialysis.  Peritoneal Dialysis Intrnational. 2014 Mar-Apr;34(2):245-7.